Metabolic Regulation of the Immune Response


8th June 2018 | Rome

Aula Convegni CNR - Piazzale Aldo Moro, Ingresso via dei Marruccini

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Organising Committee

  • John Hiscott
    Istituto Pasteur Italia, Rome (Italy)
  • Angela Santoni
    Sapienza University, Rome (Italy)
  • Francesca Di Rosa
    Institute of Molecular Biology and Pathology, CNR, Rome (Italy)

Invited Speakers

  • Andrew Bowie
    School of Biochemistry & Immunology
    Trinity College Dublin, Ireland
  • Peter Murray
    Max Planck Institute
    Martinsried, Germany
  • Olaf Gross
    Freiburg University, Germany
  • Giuseppe Matarese
    IEOS - CNR University of Naples, "Federico II", Italy
  • Ursula Grohmann
    University of Perugia
    Dept. of Pathology, Italy
  • Antonio Sica
    University Piemonte Orientale "A. Avogadro" - Novara, Italy

Program

Morning Session
Chair: John Hiscott
(Istituto Pasteur italia, Rome, Italy)
10:00 – 10:15
John Hiscott
Introduction
10:15 – 11:00
Dr. Antonio Sica
(Piemonte Orientale University, Novara, Italy)
Metabolic control of the mobilization of myeloid suppressor cells in cancer
11:00 – 11:45
Dr. Andrew Bowie
(Trinity College Dublin, Ireland)
SARM regulates cell fate after inflammasome activation: new roles for an ancient protein
11:45 – 12:10
Dr. David Olagnier
(Aarhus University, Denmark)
Nrf2 is a negative regulator of STING during metabolic reprogramming
12:10 – 12:30
Dr. Alessio Paone
(Sapienza University, Rome, Italy)
Linking inflammation to prostate cancer: innate immune receptor stimulation triggers metabolic re-programming in non-immune cells
12:30- 13:45
Lunch & Coffee
Afternoon Session
Chair: Francesca Di Rosa
(Institute of Molecular Biology and Pathology, CNR, Rome, Italy)
13:45 – 14:30
Dr. Olaf Gross
(Freiburg University, Germany)
Simultaneous targeting of cancer and immune cell metabolism: a topical approach
14:30 – 15:15
Dr. Ursula Grohmann
(University of Perugia, Italy)
Targeting IDO1 dynamics in autoimmunity
15:15 – 15:40
Dr. Francesca Fallarino
(University of Perugia, Italy)
A novel tryptophan metabolite-dependent circuit in DC1 promotes regulatory DC2 leading to suppression of autoimmune responses
15:40 – 16:00
Break
16:00 – 16:45
Dr. Giuseppe Matarese
(University of Naples Federico II & IEOS-CNR, Italy)
A role for overnutrition and obesity in the autoimmunity epidemic
16:45 – 17:10
Dr. Silvia Piconese
(Sapienza University & Ist Pasteur, Rome, Italy)
Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth 
17:10 – 18:00
Dr. Peter Murray
(Max Planck Inst., Martinsreid, Germany)
Immunoregulation by amino acid metabolism